Profiling the Activity & Selectivity of Transcription Factor Therapeutics Using Functional Proteomics

Time: 10:00 am
day: Day One


• Proteomics of chromatin associated proteins has proven historically challenging
• Understand how the MARMOT platform allows unbiased, comprehensive profiling of TF activity in response to perturbations in live, unmodified human cells
• Use the MARMOT platform to uncover interesting mechanisms known drugs and discover new compounds capable of interacting with TFs