Targeting Xenobiotic Nuclear Receptor-Mediated Transcription to Increase Drug Efficacy & Reduce Drug Toxicity

Time: 1:30 pm
day: Day One

Details:

• Xenobiotic nuclear receptors transcriptionally regulate drug metabolism and therapeutic responses
• By using both hypothesis-driven and technology-enabled approaches, it is feasible to design small molecules to turn on, block or turn off transcription
• Highlighting how it is feasible to pharmacologically attenuate xenobiotic receptor-mediated drug toxicity and liver injury

Speakers: