TEAD & The HIPPO Pathway

Time: 3:00 pm
day: Day Two


• TEAD (Transcriptional Enhanced Associate Domain) is an important component of the Hippo signalling system, which is dysregulated in solid malignancies including mesothelioma and several squamous cell carcinomas
• TEAD is also being linked to the development of resistance to targeted therapy, such as those for EGFR-mutated and KRAS-mutated lung cancer