Taosheng Chen

Taosheng Chen

Company: St. Jude Children’s Research Hospital

Job title: Director - High Throughput Bioscience & Chemical Biology


Targeting Xenobiotic Nuclear Receptor-Mediated Transcription to Increase Drug Efficacy & Reduce Drug Toxicity 1:30 pm

• Xenobiotic nuclear receptors transcriptionally regulate drug metabolism and therapeutic responses • By using both hypothesis-driven and technology-enabled approaches, it is feasible to design small molecules to turn on, block or turn off transcription • Highlighting how it is feasible to pharmacologically attenuate xenobiotic receptor-mediated drug toxicity and liver injuryRead more

day: Day One

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